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A higher viral load

Delta is not only more transmissible than previous SARS-CoV-2 variants, it can also cause more severe disease. People infected with the Delta variant harbor about 1,000 times the number of viral particles (which experts call the “viral load”) in their nasal swab compared to those infected with another strain, “which is an enormous increase,” says Eric Topol, the founder and director of the Scripps Research Translational Institute, who was not involved in this study.

One reason for this is that the Delta variant replicates more quickly in the nose. A study, not yet peer reviewed has shown that the Delta variant took an average of four days to reach detectable levels after exposure to a sick person, compared to about six days for the original Wuhan virus.Male Sex Dolls

Even after vaccination, Delta infections produced a 10-fold higher viral load than non-Delta infections. In fact several recent studies, none peer reviewed yet, show that vaccinated people carry the same viral load as the unvaccinated. “We are seeing infections and seeing the large number of people being infected by a single case, which is quite worrying. It means that the virus is highly transmissible and is able to avoid … vaccine-induced immunity,” said Ravindra Gupta, a clinical microbiologist at the University of Cambridge, who led the study that is not yet peer reviewed.Melina Sex Doll

Delta is also better at destroying cells because of a mutation at position 681 of its spike protein, which is fast becoming common in other variants around the globe and is thought to be an evolutionary game changer. This P681R mutation makes it easier for Delta and the related Kappa variants to invade the host cell by fusing infected cells into structures called syncytium, which is a way of accelerating infection. Syncytia are also formed by other viruses such as HIV. “We found in cell culture experiments that Delta variant shows bigger syncytia when compared to SARS-CoV-2,” explained Kei Sato, a virologist at The University of Tokyo, Japan.Mini Sex Dolls

The Delta variant has also undergone multiple mutations in its spike protein that seem to improve the virus’s ability to bind to the ACE2 receptor and evade theimmune response.